MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c) is a 16-amino-acid mitochondrial-derived peptide that has emerged as one of the most significant molecules in longevity and metabolic medicine. It activates AMPK (the cellular energy sensor and repair switch), improves insulin sensitivity, enhances exercise capacity, promotes mitochondrial biogenesis, and has been shown to reverse age-related physical decline in animal models.
MOTS-c helps regulate energy use, glucose metabolism, and cellular stress responses.
